|
|
(R)-2-hydroxyglutarate + NAD+ <=> 2-oxoglutarate + NADH + H+
|
1.1.1.399
2-oxoglutarate reductase
1.1.1.95
phosphoglycerate dehydrogenase
1.1.99.2
L-2-hydroxyglutarate dehydrogenase
|
–
–
–
|
| |
BRENDA:
BR51640
KEGG:
R11337
MetaCyc:
KETOGLUTREDUCT-RXN
SABIO-RK:
15201
|
|
|
|
L-aspartate <=> NH3 + fumarate
|
4.3.1.1
aspartate ammonia-lyase
4.3.1.2
methylaspartate ammonia-lyase
|
–
–
|
| |
BRENDA:
BR481
KEGG:
R00490
MetaCyc:
ASPARTASE-RXN
SABIO-RK:
922
|
|
|
|
L-glutamine + pyruvate <=> 2-Oxoglutaramate + L-alanine
|
2.6.1.15
glutamine---pyruvate transaminase
2.6.1.51
serine---pyruvate transaminase
|
–
–
|
| |
BRENDA:
BR47673
KEGG:
R00576
MetaCyc:
GLUTAMINE--PYRUVATE-AMINOTRANSFERASE-RXN
SABIO-RK:
977
|
|
|
|
succinate_semialdehyde + NADP+ + H2O <=> NADPH + succinate + H+
|
1.1.1.21
aldose reductase
1.2.1.16
succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26
2,5-dioxovalerate dehydrogenase
1.2.1.79
succinate-semialdehyde dehydrogenase (NADP+)
|
–
–
–
–
–
|
| |
BRENDA:
BR29388
KEGG:
R00714
MetaCyc:
RXN0-5293;
SUCCSEMIALDDEHYDROG-RXN
SABIO-RK:
1086
|
|
|
|
NADP+ + H2O + L-glutamate <=> NADPH + 2-oxoglutarate + NH3 + H+
|
1.4.1.13
glutamate synthase (NADPH)
1.4.1.2
glutamate dehydrogenase
1.4.1.3
glutamate dehydrogenase [NAD(P)+]
1.4.1.4
glutamate dehydrogenase (NADP+)
|
–
–
–
–
|
| |
BRENDA:
BR36869;
BS397591-a
KEGG:
R00248
MetaCyc:
GLUTAMATE-DEHYDROGENASE-NADP+-RXN;
GLUTDEHYD-RXN;
RXN-20084
SABIO-RK:
757
|
|
|
|
L-threo-3-methylaspartate <=> NH3 + mesaconate
|
4.3.1.2
methylaspartate ammonia-lyase
|
–
|
| |
BRENDA:
BR487
KEGG:
R03696
MetaCyc:
METHYLASPARTATE-AMMONIA-LYASE-RXN
|
|
|
|
butyryl-CoA + acetate <=> Butyrate + acetyl-CoA
|
2.8.3.1
propionate CoA-transferase
2.8.3.14
5-hydroxypentanoate CoA-transferase
2.8.3.8
acetate CoA-transferase
2.8.3.9
butyrate---acetoacetate CoA-transferase
|
–
–
–
–
|
| |
BRENDA:
BS358809
KEGG:
R01179
MetaCyc:
R11-RXN
|
|
|
|
4-aminobutanoate + 2-oxoglutarate <=> succinate_semialdehyde + L-glutamate
|
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.22
(S)-3-amino-2-methylpropionate transaminase
2.6.1.29
diamine transaminase
2.6.1.48
5-aminovalerate transaminase
|
–
–
–
–
–
|
| |
BRENDA:
BR47437
KEGG:
R01648
MetaCyc:
GABATRANSAM-RXN
SABIO-RK:
1785
|
|
|
|
L-glutamine + H2O <=> L-glutamate + NH3
|
1.4.1.13
glutamate synthase (NADPH)
1.4.1.14
glutamate synthase (NADH)
1.4.7.1
glutamate synthase (ferredoxin)
2.3.2.2
gamma-glutamyltransferase
2.4.2
2.4.2.14
amidophosphoribosyltransferase
3.4.11.17
tryptophanyl aminopeptidase
3.5.1.1
asparaginase
3.5.1.2
glutaminase
3.5.1.38
glutamin-(asparagin-)ase
3.5.1.43
peptidyl-glutaminase
3.5.1.44
protein-glutamine glutaminase
4.3.1.B2
4.3.2.10
imidazole glycerol-phosphate synthase
4.3.3.6
pyridoxal 5'-phosphate synthase (glutamine hydrolysing)
6.3.4.2
CTP synthase (glutamine hydrolysing)
6.3.5.13
lipid II isoglutaminyl synthase (glutamine-hydrolysing)
6.3.5.2
GMP synthase (glutamine-hydrolysing)
6.3.5.4
asparagine synthase (glutamine-hydrolysing)
6.3.5.5
carbamoyl-phosphate synthase (glutamine-hydrolysing)
6.3.5.6
asparaginyl-tRNA synthase (glutamine-hydrolysing)
6.3.5.7
glutaminyl-tRNA synthase (glutamine-hydrolysing)
|
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR22683
KEGG:
R00256
MetaCyc:
GLUTAMIN-RXN
SABIO-RK:
762
|
|
|
|
(+)-citramalate <=> pyruvate + acetate
|
4.1.3.1
isocitrate lyase
4.1.3.22
citramalate lyase
|
–
–
|
| |
BRENDA:
BR3370
KEGG:
R00325
MetaCyc:
CITRAMALATE-LYASE-RXN
|
|
|
|
(R)-2-hydroxyglutaryl-1-CoA <=> H2O + glutaconyl-CoA
|
4.2.1
4.2.1.167
(R)-2-hydroxyglutaryl-CoA dehydratase
|
–
–
|
| |
BRENDA:
BR51549
KEGG:
R03937
MetaCyc:
RXN-1083
|
|
|
|
L-glutamate + NAD+ <=> L-glutamine + 2-oxoglutarate + NADH + H+
|
1.4.1.13
glutamate synthase (NADPH)
1.4.1.14
glutamate synthase (NADH)
|
–
–
|
| |
BRENDA:
BR36862
KEGG:
R00093
MetaCyc:
GLUTAMATE-SYNTHASE-NADH-RXN
SABIO-RK:
675
|
|
|
|
crotonyl-CoA + reduced_acceptor <=> butyryl-CoA + oxidized_acceptor
|
1.3.1.8
acyl-CoA dehydrogenase (NADP+)
1.3.8.1
short-chain acyl-CoA dehydrogenase
|
–
–
|
| |
BRENDA:
BS370908
|
|
|
|
succinate_semialdehyde + NAD+ + H2O <=> NADH + succinate + H+
|
1.2.1.16
succinate-semialdehyde dehydrogenase [NAD(P)+]
1.2.1.19
aminobutyraldehyde dehydrogenase
1.2.1.21
glycolaldehyde dehydrogenase
1.2.1.24
succinate-semialdehyde dehydrogenase (NAD+)
1.2.1.26
2,5-dioxovalerate dehydrogenase
1.2.1.3
aldehyde dehydrogenase (NAD+)
1.2.1.79
succinate-semialdehyde dehydrogenase (NADP+)
1.2.1.88
L-glutamate gamma-semialdehyde dehydrogenase
|
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR29388-a
KEGG:
R00713
MetaCyc:
RXN0-5293_WOP;
SUCCINATE-SEMIALDEHYDE-DEHYDROGENASE-RXN
SABIO-RK:
1085
|
|
|
|
H+ + L-glutamate <=> CO2 + 4-aminobutanoate
|
4.1.1.15
glutamate decarboxylase
4.1.1.25
tyrosine decarboxylase
4.1.1.29
sulfinoalanine decarboxylase
|
–
–
–
|
| |
BRENDA:
BR275
KEGG:
R00261
MetaCyc:
GLUTDECARBOX-RXN
SABIO-RK:
766
|
|
|
|
2-Oxoglutaramate + H2O <=> 2-oxoglutarate + NH3
|
3.5.1.111
2-oxoglutaramate amidase
3.5.1.3
omega-amidase
3.5.1.36
N-methyl-2-oxoglutaramate hydrolase
|
–
–
–
|
| |
BRENDA:
BR50321
KEGG:
R00269
MetaCyc:
RXN-13072
SABIO-RK:
771
|
|
|
|
glutaconyl-CoA + H+ + Na+ <=> CO2 + crotonyl-CoA + Na+
|
7.2.4.5
glutaconyl-CoA decarboxylase
|
–
|
| |
BRENDA:
BR48314
MetaCyc:
RXN-19739
|
|
|
|
NAD+ + H2O + L-glutamate <=> NADH + 2-oxoglutarate + NH3 + H+
|
1.4.1.14
glutamate synthase (NADH)
1.4.1.2
glutamate dehydrogenase
1.4.1.3
glutamate dehydrogenase [NAD(P)+]
1.4.1.4
glutamate dehydrogenase (NADP+)
1.4.1.5
L-amino-acid dehydrogenase
|
–
–
–
–
–
|
| |
BRENDA:
BR36868
KEGG:
R00243
MetaCyc:
GLUTAMATE-DEHYDROGENASE-NADP+-RXN_WOP;
GLUTAMATE-DEHYDROGENASE-RXN
SABIO-RK:
755
|
|
|
|
L-glutamate + oxidized_ferredoxin <=> 2-oxoglutarate + L-glutamine + reduced_ferredoxin_[iron-sulfur]_cluster + H+
|
1.4.7.1
glutamate synthase (ferredoxin)
|
–
|
| |
BRENDA:
BR36886
KEGG:
R00021
MetaCyc:
GLUTAMATE-SYNTHASE-FERREDOXIN-RXN
|
|
|
|
L-aspartate + 2-oxoglutarate <=> oxaloacetate + L-glutamate
|
2.6.1.1
aspartate transaminase
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.2
alanine transaminase
2.6.1.39
2-aminoadipate transaminase
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.5
tyrosine transaminase
2.6.1.57
aromatic-amino-acid transaminase
2.6.1.75
cysteine-conjugate transaminase
2.6.1.78
aspartate---prephenate aminotransferase
2.6.1.79
glutamate---prephenate aminotransferase
|
–
–
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR47671;
BS377429
KEGG:
R00355
MetaCyc:
ASPAMINOTRANS-RXN;
RXN-13697
SABIO-RK:
825
|
|
|
|
acetyl-CoA + (R)-2-hydroxyglutarate <=> acetate + (R)-2-hydroxyglutaryl-1-CoA
|
2.8.3.12
glutaconate CoA-transferase
|
–
|
| |
BRENDA:
BS360577
MetaCyc:
RXN-1082
|
|
|
|
ATP + L-glutamate + tRNAMet <=> AMP + diphosphate + Glu-tRNAGln
|
6.1.1.17
glutamate---tRNA ligase
6.1.1.18
glutamine---tRNA ligase
6.1.1.24
glutamate---tRNAGln ligase
6.1.1.6
lysine---tRNA ligase
6.1.1.B3
|
–
–
–
–
–
|
| |
BRENDA:
BR44350
|
|
|
|
NH3 + L-glutamate + ATP <=> H+ + L-glutamine + ADP + phosphate
|
6.3.1.2
glutamine synthetase
|
–
|
| |
BRENDA:
BR6443
KEGG:
R00253
MetaCyc:
GLUTAMINESYN-RXN
SABIO-RK:
760
|
|
|
|
L-glutamate <=> D-glutamate
|
5.1.1.10
amino-acid racemase
5.1.1.3
glutamate racemase
5.1.1.9
arginine racemase
|
–
–
–
|
| |
BRENDA:
BR171
KEGG:
R00260
MetaCyc:
GLUTRACE-RXN
SABIO-RK:
765
|
|
|
|
4-aminobutanoate + pyruvate <=> succinate_semialdehyde + L-alanine
|
2.6.1.116
6-aminohexanoate aminotransferase
2.6.1.18
beta-alanine---pyruvate transaminase
2.6.1.19
4-aminobutyrate---2-oxoglutarate transaminase
2.6.1.40
(R)-3-amino-2-methylpropionate---pyruvate transaminase
2.6.1.96
4-aminobutyrate---pyruvate transaminase
|
–
–
–
–
–
|
| |
BRENDA:
BR50304
KEGG:
R10178
MetaCyc:
RXN-6902
|
|
|
|
L-threo-3-methylaspartate <=> L-glutamate
|
5.4.99.1
methylaspartate mutase
|
–
|
| |
BRENDA:
BR33
KEGG:
R00262
MetaCyc:
METHYLASPARTATE-MUTASE-RXN
SABIO-RK:
767
|
|
|
|
L-glutamine + L-Glutamyl-tRNA(Gln) + ATP + H2O <=> L-glutamate + glutaminyl-tRNAGln + phosphate + ADP + H+
|
6.3.5.6
asparaginyl-tRNA synthase (glutamine-hydrolysing)
6.3.5.7
glutaminyl-tRNA synthase (glutamine-hydrolysing)
|
–
–
|
| |
BRENDA:
BR44353
KEGG:
R03905
MetaCyc:
6.3.5.7-RXN
SABIO-RK:
3650
|
|
|
|
(+)-citramalate <=> H2O + mesaconate
|
4.2.1.2
fumarate hydratase
4.2.1.34
(S)-2-methylmalate dehydratase
|
–
–
|
| |
BRENDA:
BR414
KEGG:
R03693
MetaCyc:
S-2-METHYLMALATE-DEHYDRATASE-RXN
|
|
|
|
L-glutamate + NADP+ <=> H+ + L-glutamine + 2-oxoglutarate + NADPH
|
1.4.1.13
glutamate synthase (NADPH)
1.4.1.B5
|
–
–
|
| |
BRENDA:
BR36861
KEGG:
R00114
MetaCyc:
GLUTAMATESYN-RXN
SABIO-RK:
694
|
|
|
|
NADP+ + 4-hydroxybutyrate <=> H+ + NADPH + succinate_semialdehyde
|
1.1.1
1.1.1.19
glucuronate reductase
1.1.1.2
alcohol dehydrogenase (NADP+)
1.1.1.26
glyoxylate reductase
1.1.1.61
4-hydroxybutyrate dehydrogenase
1.1.1.79
glyoxylate reductase (NADP+)
1.1.1.B47
1.1.1.co
|
–
–
–
–
–
–
–
–
|
| |
BRENDA:
BR51069
KEGG:
R09281
MetaCyc:
RXN-11002
SABIO-RK:
10705
|
|
